If interested, read the article An ER Doctor in NO suggests a clinical pattern for covid-19 in Uncommon Descent. The situation there looks bad in my 100% layman eyes… but you can read what he says himself.
Note that, from the doctor:
worldwide 86% of covid 19 patients that go on a vent die. Seattle reporting 70%. Our hospital has had 5 deaths and one patient who was extubated. Extubation happens on day 10 per the Chinese and day 11 per Seattle.
Plaquenil which has weak ACE2 blockade doesn’t appear to be a savior of any kind in our patient population. Theoretically, it may have some prophylactic properties but so far it is difficult to see the benefit to our hospitalized patients, but we are using it and the studies will tell. With Plaquenil’s potential QT prolongation and liver toxic effects (both particularly problematic in covid 19 patients), I am not longer selectively prescribing this medication as I stated on a previous post.
And from the commentator
Okay, here they see a pattern, with an estimated breakdown of the population mild/severe/critical. 81/14/5. He has tried Hydrochloroquine and z-pac (not clear if this is a cocktail) but is not seeing magic from it. That’s important too.
This is a world war with a virus that is achieving lodgements and is breaking out again and again. We have to find which drugs — individual and cocktail — of the about 69 being tried will provide robust treatments. Where, I am seeing that already the strain count is up to three at least. Let’s hope resistance to drugs isn’t showing up already at trials stage — if THAT is happening, I think I may become open to the theory that this is a biowar exercise that got out in the wild. Anyway, we have a fight on our hands. END
We will see what we will see.
The young are not under direct threat, but should be cautious: already, a 31 year old female co-worker in the hospital, no conditions, has fallen ill to the disease.
Waiting for that fast, cheap, accurate, and easy-to-find COVID-19 test, President Trump.
(And I’m speaking as a media cynic!)
Note: a bit more from the comments:
Plaquenil which has weak ACE2 blockade doesn’t appear to be a savior of any kind in our patient population. Theoretically, it may have some prophylactic properties but so far it is difficult to see the benefit to our hospitalized patients, but we are using it and the studies will tell.,,,
We are also using Azithromycin, but are intermittently running out of IV.
Sigh,,, Per the studies,
New York is moving at breakneck speed to test antimalarial drugs,,,
Such an undertaking “is something that normally would have been done in six to nine months and we’re doing it in three or four days,”,,,
According to the state, three drugs will be used: hydroxychloroquine, chloroquine — both antimalarial drugs — and the antibiotic azithromycin. The first group of patients will receive hydroxychloroquine and azithromycin, a combination that proved effective in a small, controversial study in France.
So, keep your eyes open.